Research Specialist (Bioinformatics, Computational Biology)

Research Specialist (Bioinformatics, Computational Biology)

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Employers By State in 2021.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

COVID-19 vaccination is a requirement for all positions at the University of Pennsylvania. New hires are expected to be fully vaccinated before beginning work at the University. For more information about Penn's vaccine requirements and the use of Penn Open Pass, visit the Penn COVID-19 Response website for the latest information.

Posted Job Title
Research Specialist (Bioinformatics, Computational Biology)

Job Profile Title
Research Specialist B

Job Description Summary
The Modzelewski Lab at the University of Pennsylvania Department of Biomedical Sciences in the School of Veterinary Medicine is recruiting a Researcher Specialist B, C or D (Bioinformatician, Computational Biologist, BioStatistician) to join an exciting new NIH-NICHD funded project. Our work focuses on the exciting and emerging role of retrotransposons in early development and disease using mouse as a model system along with comparative biology using various mammalian species to learn about human health and reproduction.

Job Description

Research Specialist will be involved in planning and conducting ongoing research to study retrotransposon reactivation in development and disease in a team setting. The candidate will be responsible for the majority of the bioinformatics efforts of the team, working closely with wet-bench scientists and bioinformaticians from collaborating labs. Understanding the biological questions and providing rigorous statistical and bioinformatic expertise is a requirement of this position with a goal to discover new therapeutic targets in disease, cancer and fertility treatments. The candidate should have statistics and bioinformatics experience, basic programming skills (familiarity with python, R, and bash), and a background or strong interest in developmental biology, epigenetics, immunology, or cancer immunotherapy. Candidate will be involved in tool development for analyzing large volumes of high-throughput experimental data including but not limited to single-cell genomics and imaging measurements and participating in subsequent data analysis and data integration. Contributing to maintenance of multiomic single-cell genomics and imaging data analysis pipelines. The candidate will manage large repositories of sequence data, and perform analyses on different types of sequencing datasets, including but not limited to CUT & RUN, ChIP-Seq, RNA-seq, ATAC-Seq, and HiC. The individual will also assist in writing manuscripts and grants, with a focus on the statistical and bioinformatics aspects. Opportunities for training and supervising undergraduate and graduate students and interfacing with existing postdoctoral fellows and students in the laboratory. Close partnership with Principal Investigator to ensure success of all research studies. Experimental planning (wet lab) and execution is preferred but not required.


Specialist B : Bachelor's Degree in computational or life sciences with at least 2-3 years of relevant experience or an equivalent combination of education and experience.

Specialist C : Master's Degree in computational or life sciences with at least 2-3 years of relevant experience or an equivalent combination of education and experience.

Specialist D : Master's Degree in computational or life sciences with at least 4-5 years of relevant experience or an equivalent combination of education and experience. PhD is a plus.

General: Proficiency in Python, R programing and an active interest in bioinformatics, genomics, data visualization, or machine learning applications. Basic system administration basic knowledge and experience with data visualization and/or server-side programming such as PHP, Bash, node.js, D3.js are preferred. Experience working with large genomic sequence data is preferred. Ability to write clear, concise, and efficient code with documentation. Position encourages a hybrid of Wet and Dry Lab, but very flexible. Previous mouse handling experience is a plus but not essential.

Specialist B : Targeted pay range: $37,220.00 - $56,087.33

Specialist C : Targeted pay range: $43,919.00 - $66,183.00

Specialist D : Targeted pay range: $51,824.00 - $78,096.00

This Targeted Pay Range is only applicable to this job posting. All salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.

Job Location - City, State
Philadelphia, Pennsylvania

Department / School
School of Veterinary Medicine

Pay Range
$37,220.00 - $56,087.33
Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, as well as internal and market factors and grade profile.

Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits
  • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
  • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
  • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.
  • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

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